BRITE is housed in a $20.1 million facility on the campus of North Carolina Central University. This state-of-the-art facility was created with funding from the GoldenLEAF Foundation, an organization responsible for investing North Carolina’s tobacco settlement funds in economic development initiatives.
BRITE features 21,000 square feet of classroom and office space, as well as 31,000 square feet of laboratory space for faculty and students to conduct applied research in areas related to biomanufacturing and biotechnology. In addition there are common equipment rooms and core laboratories typical of those found in biotech companies – offering our students a chance to obtain hands-on experience prior to pursuing life science careers.
- Drug Discovery Core Facility – Assay development and high throughput screening (HTS) for drug discovery. The drug discovery core is a state-of-the-art HTS facility with over 450,000 compound small molecule chemical libraries. The core features industry standard equipment including fluorescent and luminescent readers such as PheraStar Envision, Victor, Microbeta, Spectramax384, and FLIPR Tetra. Liquid handling is accomplished with a Beckman Coulter Biomek NX, Biomek 3000, Biomek 2000, and Tecan Aquarius 384 multichannel pipettor.
- Protein Expression, Purification and Formulation Core Facility – Capable of expressing and purifying large quantities of recombinant proteins for biopharmaceutical research and investigating protein stability/aggregation using advanced techniques such as differential scanning calorimetry, self-interaction chromatography, dynamic light scattering, circular dichroism, etc.
- Imaging Core Facility – For high-resolution imaging of biological samples, including fluorescence microscopy, confocal microscopy, DIC, Widefield, etc.
- Monoclonal Antibody Production Core Facility – For production of monoclonal antibodies to be used in research and formulation studies. This Core generates and purifies monoclonal antibodies. Equipment includes a Fluorescence Activated Cell Sorting (FACS) system for the selection of high-affinity clones.
- Technology Core Facility – Features atomic force microscopy and biosensor development.
Students also benefit from the integration of our facilities with NCCU’s existing Mary M. Townes Science Building (opened in 2005). Together, the BRITE and Townes buildings represent a $56 million, 180,000 square foot science complex where future history-making scientists train.