North Carolina Central University


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Found 16 results

Filters: Author is Zheng, W.  [Clear All Filters]
2007
Zhang S, Wei L, Bastow K, Zheng W, Brossi A, Lee K, Tropsha A.  2007.  Antitumor agents 252. Application of validated QSAR models to database mining: discovery of novel tylophorine derivatives as potential anticancer agents.. J Comput Aided Mol Des. 21:97--112. Abstract
2006
Johnson SR, Zheng W.  2006.  Recent progress in the computational prediction of aqueous solubility and absorption.. AAPS J. 8:E27--E40. Abstract
2005
Kovatcheva A, Golbraikh A, Oloff S, Feng J, Zheng W, Tropsha A.  2005.  QSAR modeling of datasets with enantioselective compounds using chirality sensitive molecular descriptors.. SAR QSAR Environ Res. 16:93--102. Abstract
2004
Kovatcheva A, Golbraikh A, Oloff S, Xiao Y, Zheng W, Wolschann P, Buchbauer G, Tropsha A.  2004.  Combinatorial QSAR of ambergris fragrance compounds.. J Chem Inf Comput Sci. 44:582--595. Abstract
Zheng W.  2004.  Simulated annealing: an effective stochastic optimization approach to computational library design.. Methods Mol Biol. 275:379--398. Abstract
2002
Tropsha A, Zheng W.  2002.  Rational principles of compound selection for combinatorial library design.. Comb Chem High Throughput Screen. 5:111--123. Abstract
2001
Reynolds CH, Tropsha A, Pfahler LB, Druker R, Chakravorty S, Ethiraj G, Zheng W.  2001.  Diversity and coverage of structural sublibraries selected using the SAGE and SCA algorithms.. J Chem Inf Comput Sci. 41:1470--1477. Abstract
Tropsha A, Zheng W.  2001.  Identification of the descriptor pharmacophores using variable selection QSAR: applications to database mining.. Curr Pharm Des. 7:599--612. Abstract
2000
Zheng W, Hung ST, Saunders JT, Seibel GL.  2000.  PICCOLO: a tool for combinatorial library design via multicriterion optimization.. Pac Symp Biocomput. :588--599. Abstract
1999
Hoffman B, Cho SJ, Zheng W, Wyrick S, Nichols DE, Mailman RB, Tropsha A.  1999.  Quantitative structure-activity relationship modeling of dopamine D(1) antagonists using comparative molecular field analysis, genetic algorithms-partial least-squares, and K nearest neighbor methods.. J Med Chem. 42:3217--3226. Abstract
Zheng W, Cho SJ, Waller CL, Tropsha A.  1999.  Rational combinatorial library design. 3. Simulated annealing guided evaluation (SAGE) of molecular diversity: a novel computational tool for universal library design and database mining.. J Chem Inf Comput Sci. 39:738--746. Abstract
1998
Cho SJ, Zheng W, Tropsha A.  1998.  Focus-2D: a new approach to the design of targeted combinatorial chemical libraries.. Pac Symp Biocomput. :305--316. Abstract
Zheng W, Cho SJ, Tropsha A.  1998.  Rational combinatorial library design. 1. Focus-2D: a new approach to the design of targeted combinatorial chemical libraries.. J Chem Inf Comput Sci. 38:251--258. Abstract
Cho SJ, Zheng W, Tropsha A.  1998.  Rational combinatorial library design. 2. Rational design of targeted combinatorial peptide libraries using chemical similarity probe and the inverse QSAR approaches.. J Chem Inf Comput Sci. 38:259--268. Abstract
1997
Zheng W, Cho SJ, Vaisman II, Tropsha A.  1997.  A new approach to protein fold recognition based on Delaunay tessellation of protein structure.. Pac Symp Biocomput. :486--497. Abstract
1996
Tropsha A, Singh RK, Vaisman II, Zheng W.  1996.  Statistical geometry analysis of proteins: implications for inverted structure prediction.. Pac Symp Biocomput. :614--623. Abstract