Li-An Yeh, Ph.D.
Director, Professor of Pharmaceutical Sciences
Systematic discovery of molecules which enhance the NGF-like growth factors and the elucidation of molecular mechanism for the signal amplification of these molecules will further aid to the therapeutic intervention of neurodegeneration, such as AD, Parkinson’s disease, ALS and Huntington’s disease.
Role of Tau in Alzheimer’s Disease
The elucidation and the kinetics and mechanism of Tau phosphorylation leading to aggregation and binding to microtubules will further shed some light in the role of Tau in Alzheimer’s disease and other neurodegenerative diseases.