John E. Scott, Ph.D.
Associate Professor of Pharmaceutical Sciences

• Earned B.S. in Biochemistry at University of Illinois and Ph.D. in Microbiology and Immunology at Duke University
• Spent seven years in industry – five and half years at Eli Lilly and Company as a Principal Scientist in Drug Discovery and two and half years at Helios Pharmaceuticals as a Staff Scientist
• Contact: jscott@nccu.edu or 919-530-7569

PON1 Transcriptional Regulation
PON1 appears to protect against atherosclerosis (i.e. hardening of the arteries) and the expression of PON1 varies considerably among individuals. The goal of this research is to better understand the regulation of
PON1 expression by elucidating important regulatory sequences in the PON1 promoter.

Regulation of PON1 Expression by Cytokines
The goal of this project is to evaluate the effect of various cytokines on the expression of PON1.