Carla Edge Oldham, Ph.D.
Assistant Research Professor
Investigation of the Role of CHK in Neuronal Development
This project explores the role of Csk Homologous Kinase (CHK) in neurite outgrowth and signaling pathways as well as the translocation of CHK. The overall goal is to elucidate the role(s) of CHK in neuronal cell signaling in order to
1) develop a HTS screening assay to detect the absence or presence of CHK in tumor cells and
2) find small molecules that can inhibit or induce the expression of CHK.