North Carolina Central University

Andy Li, M.D., Ph.D

Professor of Pharmaceutical Sciences

  • Earned B.S. and M.D. in Medicine in China and completed Neuroscience doctoral work at the University of Lund in Sweden
  • Prepared for teaching career as a senior research scientist at Queens Medical Center
  • Taught at University of Hawaii for three years prior to coming to NCCU
  • Awarded a NIH/COBRE grant for 2001-2007, NIH/RCMI grant for 2001-2006 and NIH/RO1 grant for 2007-2012
  • Contact: or 919-530-6872

Mechanism and Treatment of Brain Damage After Cerebral Stroke
The core focus of this research is cell death and survival pathways, free radicals, neuro-inflammation, astrocytic response and neuro-protection after stroke. The study seeks to determine validity of the hypothesis that cerebral stroke leads to neuron damage by increasing free radical production, enhancing neuro-inflammation, suppressing cell survival pathways and causing cell death of necrosis and/or apoptosis. It is believed that agents aimed at blocking these biochemical cascades could provide protection against stroke.

Exacerbation Effects of Diabetes and Hyperglycemia on Stroke
Core focus revolves around mechanisms by which hyperglycemia mellitus enhances ischemic brain damage.  The research seeks to prove that 1) hyperglycemia enhances ischemic brain damage by causing early mitochondrial failure and 2) preservation of mitochondrial function reduces hyperglycemia enhanced damage.